ABSTRACT
The present study evaluates platelet activation following application of an Esmarch bandage and a tourniquet, procedures commonly employed to provide a bloodless operative field during limb surgery. Platelet aggregation was increased in blood samples taken from rabbits 60 min after an Esmarch bandage was applied to one thigh and immediately released. When this treatment was combined with the application of a tourniquet for 60 min, a procedure which alone did not affect platelet aggregation, results were similar to those obtained following the Esmarch bandage alone. These data suggest that tissue compression produced by application of an Esmarch bandage, but not the ischemia derived from the tourniquet, produced platelet aggregation
Subject(s)
Rabbits , Animals , Male , Bandages , Platelet Activating Factor , Tourniquets , Ischemia/complications , Platelet Aggregation , Thrombophlebitis/etiologyABSTRACT
The action of threem different topical heparinoids on the evolution of experimental thrombophlebitis was studies. Thrombophlebitis was induced in the marginal vein of the ear of rabbits by stasis and inection of hypertonic glucose solution. Forty-eight hours later animals were allocated to three treatment groups and a control group. The substances were applied over the affected vein three times a day for 6 days and the ears inspected daily by transillumination. After 7 days, the animals were killed and anatomopathological studies performed. No difference in thrombus frequency or inflamatory reaction was observed between the animals treated with heparinoids and the control group, or among the treated groups
Subject(s)
Rabbits , Animals , Heparinoids/pharmacology , Thrombophlebitis/chemically inducedABSTRACT
Por ser uma afeccao de diagnostico raro no Brasil, os autores apresentam dois casos de cisto de adventicia em arteria poplitea em pacientes masculinos, tratados no Hospital das Clinicas da Faculdade de Medicina de Botucatu. Os achados clinicos, radiologicos, histopatologicos e o tratamento sao descritos e comparados com os da literatura